What diseases are seen in annular erythema?
Erythema annularis is a skin lesion that appears as a round or annular erythema with sharp edges and a center that may fade or appear normal-colored. This symptom may be related to a variety of diseases. The following are diseases related to annular erythema and their characteristics that have been hotly discussed on the Internet in the past 10 days.
1. Common causes of annular erythema

| Disease name | Typical characteristics | Related symptoms |
|---|---|---|
| centrifugal annular erythema | Edge expansion, center fading | Mild itching or no symptoms |
| rheumatic fever | erythema migrans | Fever, joint pain, carditis |
| Lyme disease | Erythema target (EM) | History of tick bites, flu-like symptoms |
| systemic lupus erythematosus | Butterfly erythema or discoid erythema | Light sensitivity, arthritis, kidney damage |
| fungal infection | Raised edges with scales | Local itching, tendency to spread |
2. Related diseases that have been hotly discussed recently
1.Lyme disease: Lyme disease-related searches have increased recently due to climate change and increased outdoor activities. Its typical annular erythema (erythema migrans) usually appears 3-30 days after a tick bite and can reach 5-30 cm in diameter, requiring early antibiotic treatment.
2.rheumatic fever in children: Some parents shared cases on social media, reminding people to pay attention to the annular erythema (marginal erythema) that occurs after streptococcal infection, which is often accompanied by heart murmur and chorea symptoms.
3. Key points of diagnosis and identification
| Check items | meaning | Typical results |
|---|---|---|
| skin biopsy | Identify pathological type | Epidermal spongiosis/perivascular infiltration |
| ASO detection | Rheumatic Fever Screening | Elevated streptococcal antibodies |
| Lyme disease antibodies | serological diagnosis | IgM/IgG positive |
| ANA test | Autoimmune disease screening | SLE patients are mostly positive |
4. Treatment and prevention suggestions
1.Infectious diseases: Doxycycline is the first choice for Lyme disease; topical antifungals are needed for fungal infections; penicillin is needed for streptococcal infections.
2.autoimmune disease: Systemic lupus erythematosus requires immunosuppressant treatment and avoidance of sun exposure.
3.Precautions:
5. Latest research trends
According to the latest literature in PubMed, annular erythema is associated withImmune abnormalities after COVID-19The association has become a research hotspot. Some patients develop refractory annular erythema after recovery, which may be related to virus-induced vasculitis.
Note: The information in this article is integrated from WHO guidelines, UpToDate clinical database and social media health topic discussions in the past 10 days. Please follow your doctor's advice for actual diagnosis and treatment.
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